Sildenafil medicines are used for treating the symptoms of erectile dysfunction (ED) in males. These medicines overcome erection difficulties by easing the blood flow to the penile.
Lack of blood flow to the penile is the reason why men experience erectile dysfunction. But these medicines alleviate such difficulties and help achieve and sustain firmer erections.
According to various sources, the effects of sildenafil medications can remain active in the body for around 4 to 5 hours. After taking the medicine, it takes approximately 30 minutes to an hour for its effects to become active.
Sildenafil medicines overcome erection difficulties in males and alleviate the symptoms of erectile dysfunction (ED) in men. These medicines work by enhancing the flow of blood inside the penile arteries.
The blood flow to the penile gets hindered due to the formation of blockages due to plaque formation in the passages of the penile blood vessels. Sildenafil medicines open the narrowed penile arteries and increase blood flow to the penile.
In addition to treating ED, healthcare providers also prescribe Sildenafil medicines for alleviating the symptoms of pulmonary arterial hypertension (PAH).
Once the medicine is taken, it may take around 30 minutes to an hour for it to become fully active and begin its action. The effects of the pill will continue to remain for around 4 to 5 hours.
How long will the pill work depends on several factors like age, dosage, ongoing health issues, illnesses, and so on.
How does the effective time of Sildenafil get impacted?
The duration of action of Sildenafil medicines may be affected because of drug-alcohol and drug-drug interactions. The medicine may not be suitable for combining with such substances. Their interaction may trigger serious side effects or produce a delayed response.
Also, substances such as medicines, recreational drugs, etc. might lower the potency of Sildenafil when used in combination. Their mixing up can disrupt the medicinal action and the medicine will fail to deliver its required response.
Sildenafil has the key ingredient, Sildenafil Citrate, which is classified under the Phosphodiesterase type 5 (PDE5) inhibitor drugs.
Being a PDE5 inhibitor, the medicine suppresses some enzymatic action happening in the walls of penile blood vessels. It expands the constricted and narrowed arteries of the penile and enhances the blood flow through them.
The sudden increase in blood flow helps attain stronger erections. Sildenafil medicine stops PDE5 action expands the passages of the arteries and allows more blood supply inside. In this way, Sildenafil stops the action of PDE enzymes in the arteries.
How does Sildenafil treat erectile dysfunction?
Hyperactivity of PDE5 enzymes leads to plaque formation in the penile arteries. This can make the arteries get blocked and the blood flow inside gets hindered as a result. The person may struggle to get and sustain erections.
Sildenafil is a potent vasodilator, that effectively enhances the flow of blood inside by stimulating the release of a chemical called Nitric oxide (NO) into the endothelial walls of the penile arteries.
The release of nitric oxide triggers the muscle expansion of the arteries, which leads to complete arterial relaxation. The medicine expands the arteries and the blood enters inside and fills the two tubes of spongy tissues present in the penile.
As the erectile tissues swell with blood, the erections triggered will be stronger. When the blood flow happens inside adequately, the arteries become narrow and trap the blood for sustaining erections.
Sildenafil is a generic version of Viagra medicines. Besides, Viagra, sildenafil has many other alternatives. One alternative to Sildenafil is Sildisoft 50.
ED medicines deliver the required action only during sexual arousal. Their function is to boost the blood flow inside the penile and promote harder erections.
Sildenafil medications contain a key or active along with some inactive ingredients that might trigger some side effects. These side effects can be of mild to moderate intensity.
Potential side effects of Sildenafil include headaches, flushing, vomiting, rashes, sore throat, nausea, insomnia, stuffy nose or nasal congestion, blurred vision, back pain, stomachache, diarrhea, and dizziness.
Such side effects do not remain for too long. They tend to disappear in a short duration, and they fade away, the medicinal effects gradually decline.
However, if the side effects continue to remain and do not go away within a few days, one must see a healthcare provider. Men with some serious health issues must have a word with their doctor before considering Sildenafil.
